Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A middle-aged female with recurrent sinopulmonary infections: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access A middle-aged female with recurrent sinopulmonary infections a case report Umesh C Yalavarthy and Mukta Pandaf Address Department of Medicine University of Tennessee College of Medicine-Chattanooga Chattanooga TN 37403 USA Email Umesh C Yalavarthy - umesheras@ Mukta Panda - Corresponding author fEqual contributors Published 21 April 2008 Received 10 September 2007 Journal of Medical Case Reports 2008 2 117 doi 1752-1947-2-117 Accepted 21 April 2008 This article is available from http content 2 1 117 2008 Yalavarthy and Panda licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Common variable immunodeficiency CVID is a form of severe antibody deficiency with an estimated prevalence of 1 in 25 000 to 1 in 100 000. The disorder apparently results from currently undefined immune deregulations resulting in failed B-cell differentiation with impaired secretion of immunoglobulins. It has a broad range of clinical symptoms including recurrent infections of the respiratory tract chronic lung disease autoimmune diseases liver and gastrointestinal disorders granulomatous infiltrations lymphoma and solid tumors. Case presentation A 42-year-old Caucasian female presented with a one-day history of highgrade fever and productive cough associated with retrosternal chest pain. The patient had been discharged one week prior after a prolonged stay in an intensive care unit with multiorgan failure requiring temporary hemodialysis for two weeks secondary to sepsis. Past medical history was significant for chronic obstructive pulmonary disease recurrent pneumonias and recurrent sinus .
