Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: New onset diabetes complicated by haemolysis and rhabdomyolysis: a case report and review of the literature | Journal of Medical Case Reports BioMed Central Case report New onset diabetes complicated by haemolysis and rhabdomyolysis a case report and review of the literature Clare M Galtrey and Rohan Pathansali Open Access Address Department of Medicine Kings College Hospital Denmark Hill London SE5 9RS UK Email Clare M Galtrey - Rohan Pathansali - Corresponding author Published 16 May 2008 Received 26 October 2007 Journal of Medical Case Reports 2008 2 159 doi 1752-1947-2-159 Accepted 16 May 2008 This article is available from http content 2 1 159 2008 Galtrey and Pathansali licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Previously undiagnosed glucose-6-phosphate dehydrogenase G6PD deficiency can be unmasked by a diabetic crisis and both can be associated with rhabdomyolysis. The relationship between diabetes and G6PD deficiency is discussed and the possible triggers for haemolysis as outlined in this case report. The incidence of G6PD deficiency is 10 in African-American males and up to 35 in parts of Africa so an increased awareness of G6PD deficiency is important when treating diabetes in these populations. Case presentation A 54-year-old Kenyan man presented with a 3-day history of reduced appetite weakness and reduced level of consciousness as a result of a hyperglycaemic diabetic crisis with both hyperosmolarity and ketoacidosis. The patient then developed haemolysis and a raised creatine kinase level. A diagnosis of G6PD deficiency and rhabdomyolysis was made. Conclusion This case highlights the importance of simple laboratory investigations in the early identification of the rarer complications of diabetic crisis
