Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Adaptation of the QoL-AGHDA scale for adults with growth hormone deficiency in four Slavic languages | McKenna et al. Health and Quality of Life Outcomes 2011 9 60 http content 9 1 60 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Adaptation of the QoL-AGHDA scale for adults with growth hormone deficiency in four Slavic languages 1 1 1 1 2 Stephen P McKenna Jeanette Wilburn James Twiss Sigrid R Crawford Václav Hána Malgorzata Karbownik-Lewinska3 Vera Popovic4 Mikulas Pura5 and Maria Koltowska-Haggstrom6 Abstract Purpose The Quality of Life in Adult Growth Hormone Deficiency Assessment QoL-AGHDA is a disease-specific quality of life measure specific to individuals who are growth hormone deficient. The present study describes the adaptation of the QoL-AGHDA for use in the following four Slavic languages Czech Polish Serbian and Slovakian. Methods The study involved three stages in each language translation cognitive debriefing and validation. The validation stage assessed internal consistency Cronbach s alpha reproducibility test-retest reliability using Spearman s rank correlations convergent and divergent validity Correlations with the NHP and known group validity. Results The QoL-AGHDA was successfully translated into the target languages with minimal problems. Cognitive debriefing interviewees n 15-18 found the measures easy to complete and identified few problems with the content. Internal consistency Czech Republic Poland Serbia and Slovakia and reproducibility Czech Republic Poland Serbia and Slovakia were good in all adaptations. Convergent and divergent validity and known group validity data were not available for Slovakia. The QoL-AGHDA correlated as expected with the NHP scales most relevant to GHD. The QoL-AGHDA was able to distinguish between participants based on a range of variables. Conclusions The QoL-AGHDA was successfully adapted for use in the Czech Republic Poland Serbia and Slovakia. Further validation of the Slovakian version would be beneficial. The addition of these new lanaguage .