Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Feasibility, reliability and validity of health-related quality of life questionnaire among adult pulmonary tuberculosis patients in urban Uganda: cross-sectional study | Babikako et al. Health and Quality of Life Outcomes 2010 8 93 http content 8 1 93 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Feasibility reliability and validity of health-related quality of life questionnaire among adult pulmonary tuberculosis patients in urban Uganda cross-sectional study Harriet M Babikako1 Duncan Neuhauser2 Achilles Katamba3 Ezekiel Mupere4 Abstract Background Despite the availability of standard instruments for evaluating health-related quality life HRQoL the feasibility reliability and validity of such instruments among tuberculosis TB patients in different populations of sub-Saharan Africa where TB burden is of concern is still lacking. Objective We established the feasibility reliability and validity of the Medical Outcomes Survey MOS in assessing HRQoL among patients with pulmonary tuberculosis in Kampala Uganda. Methods In a cross-sectional study 133 patients with known HIV status and confirmed pulmonary TB disease were recruited from one public and one private hospital. Participants were enrolled based on duration of TB treatment according to the following categories starting therapy two months of therapy and eight completed months of therapy. A translated and culturally adapted standardized 35-item MOS instrument was administered by trained interviewers. The visual analogue scale VAS was used to cross-validate the MOS. Results The MOS instrument was highly acceptable and easily administered. All subscales of the MOS demonstrated acceptable internal consistency with Cronbach s alpha above except for role function that had . Each dimension of the MOS was highly correlated with the dimension measured concurrently using the VAS providing evidence of validity. Construct validity demonstrated remarkable differences in the functioning status and well-being among TB patients at different stages of treatment between patients attending public and private hospitals and between men and women of older age. .
