Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study | Daubin et al. Health and Quality of Life Outcomes 2011 9 35 http content 9 1 35 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older a prospective cohort study 1 1a I - 1 2 1 1 Cédric Daubin Stephanie Chevalier Amélie Séguin Cathy Gaillard Xavier Valette Fabrice Prévost 13 1 24 1 Nicolas Terzi Michel Ramakers Jean-Jacques Parienti Damien du Cheyron and Pierre Charbonneau Abstract Background The purpose of this study was to identify predictors of 3-month mortality in critically ill older persons under medical care and to assess the clinical impact of an ICU stay on physical and cognitive dependence and subjective health status in survivors. Methods We conducted a prospective observational cohort study including all older persons 75 years and older consecutively admitted into ICU during a one-year period except those admitted after cardiac arrest All patients were followed for 3 months or until death. Comorbidities were assessed using the Charlson index and physical dependence was evaluated using the Katz index of Activity of Daily Living ADL . Cognitive dependence was determined by a score based on the individual components of the Lawton index of Daily Living and subjective health status was evaluated using the Nottingham Health Profile NHP score. Results One hundred patients were included in the analysis. The mean age was years. The median Charlson index was 6 IQR 4 to 7 and the mean ADL and cognitive scores were and respectively corresponding to a population with a high level of comorbidities but low physical and cognitive dependence. Mortality was 61 100 61 at 3 months. In multivariate analysis only comorbidities assessed by the Charlson index Adjusted Odds Ratio 95 CI p and the number of organ failures assessed by the SOFA score Adjusted Odds Ratio 95 CI p were .
