Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat | BMC Plant Biology BioMed Central Open Access Methodology article A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat Cristobal Uauy1 4 Francine Paraiso1 Pasqualina Colasuonno1 2 Robert K Tran3 Helen Tsai3 Steve Berardi3 Luca Comai3 and Jorge Dubcovsky 1 4 Address Department of Plant Sciences University of California Davis CA 95616 USA 2Department of Genetics and Plant Breeding University of Bari Italy 3UC Davis Genome Center University of California Davis CA 95616 USA and 4John Innes Centre Colney Norwich NR4 7UH UK Email Cristobal Francine Paraiso - fjparaiso@ Pasqualina Colasuonno - pattybiotec@ Robert K Tran - rktran@ Helen Tsai - helen_tsai83@ Steve Berardi - Luca Comai - lcomai@ Jorge Dubcovsky - jdubcovsky@ Corresponding author Published 28 August 2009 Received 13 June 2009 BMC Plant Biology 2009 9 115 doi l47l-2229-9-ll5 Accepted 28 August 2009 This article is available from http l47l-2229 9 l 15 2009 Uauy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Wheat Triticum ssp. is an important food source for humans in many regions around the world. However the ability to understand and modify gene function for crop improvement is hindered by the lack of available genomic resources. TILLING is a powerful reverse genetics approach that combines chemical mutagenesis with a high-throughput screen for mutations. Wheat is specially well-suited for TILLING due to the high mutation densities tolerated by polyploids which allow for very efficient screens. Despite this few TILLING populations are currently available. In .
