Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evidence of recombination in Hepatitis C Virus populations infecting a hemophiliac patient | Virology Journal BioMed Central Research Evidence of recombination in Hepatitis C Virus populations infecting a hemophiliac patient Pilar Moreno1 Macarena Alvarez1 Lilia Lopez1 2 Gonzalo Moratorio1 Didier Casane3 Matias Castells1 Silvia Castro4 Juan Cristina1 and Rodney Colina 1 Address 1Laboratorio de Virologia Molecular Centro de Investigaciones Nucleares Facultad de Ciencias Universidad de la República Montevideo Uruguay 2Servicio Nacional de Sangre Montevideo Uruguay 3Laboratoire Evolution Génomes Spéciation CNRS 91198 Gif-sur- Yvette France and 4Cátedra de hemoterapia Hospital de Clinicas Montevideo Uruguay Email Pilar Moreno - pmoreno@ Macarena Alvarez - malvarez@ Lilia Lopez - llopez@ Gonzalo Moratorio - gmora@ Didier Casane - Matias Castells - mcastells@ Silvia Castro - scastro@ Juan Cristina - cristina@ Rodney Colina - rcolina@ Corresponding author Open Access Published 18 November 2009 Received 23 September 2009 Accepted 18 November 2009 Virology Journal 2009 6 203 doi I743-422X-6-203 This article is available from http content 6 1 203 2009 Moreno et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Aim Hepatitis C virus HCV infection is an important cause of morbidity and mortality in patients affected by hereditary bleeding disorders. HCV as others RNA virus exploit all possible mechanisms of genetic variation to ensure their survival such as recombination and mutation. In order to gain insight into the genetic variability of HCV virus strains circulating in hemophiliac patients we
