Báo cáo khoa học:" Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome | BioMed Central Virology Journal Open Access Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome Pruksa Nawtaisong1 2 James Keith1 Tresa Fraser1 Velmurugan Balaraman1 Andrey Kolokoltsov3 Robert A Davey3 Stephen Higgs4 Ahmed Mohammed1 Yupha Rongsriyam2 Narumon Komalamisra2 and Malcolm J Fraser Jr 1 Address Department of Biological Sciences Eck Institute of Global Health University of Notre Dame Notre Dame Indiana 46556 USA 2Department of Medical Entomology Faculty of Tropical Medicine Mahidol University Bangkok Thailand 3Department of Microbiology and Immunology University of Texas Medical Branch Galveston Texas 77555 USA and 4Department of Pathology Center for Biodefense and Emerging Infectious Diseases University of Texas Medical Branch Galveston Texas 77555 USA Email Pruksa Nawtaisong - eightam@ James Keith - jkeith@ Tresa Fraser - Velmurugan Balaraman - vbalaram@ Andrey Kolokoltsov-aakoloko@ Robert A Davey - radavey@ Stephen Higgs - sthiggs@ Ahmed Mohammed - amohoammed00@ Yupha Rongsriyam - r_yupha@ Narumon Komalamisra - Malcolm J Fraser - Corresponding author Published 4 June 2009 Received 6 August 2008 Accepted 4 June 2009 Virology Journal 2009 6 73 doi l 743-422X-6-73 This article is available from http content 6 1 73 2009 Nawtaisong et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Outbreaks of Dengue impose a heavy economic burden on developing countries in terms of vector control and human morbidity. Effective vaccines against all four serotypes of Dengue are in .

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