Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado, New Mexico and Montana | Virology Journal BioMed Central Research Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado New Mexico and Montana William C Black IV1 Jeffrey B Doty2 Mark T Hughes2 Barry J Beaty2 and Charles H Calisher 2 Open Access Address Department of Microbiology Immunology Pathology College of veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins Colorado USA and 2Arthropod-borne and Infectious Diseases Laboratory Department of Microbiology Immunology Pathology College of veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins Colorado USA Email William C Black - wcb4@ Jeffrey B Doty - jdoty@ Mark T Hughes - mthughes@ Barry J Beaty - bbeaty@ Charles H Calisher - calisher@ Corresponding author Published 14 July 2009 Received 8 April 2009 Virology Journal 2009 6 102 doi 1743-422X-6-102 Accepted I4 July 2009 This article is available from http content 6 1 102 2009 Black et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background All viruses in the family Bunyaviridae possess a tripartite genome consisting of a small a medium and a large RNA segment. Bunyaviruses therefore possess considerable evolutionary potential attributable to both intramolecular changes and to genome segment reassortment. Hantaviruses family Bunyaviridae genus Hantavirus are known to cause human hemorrhagic fever with renal syndrome or hantavirus pulmonary syndrome. The primary reservoir host of Sin Nombre virus is the deer mouse Peromyscus maniculatus which is widely distributed in North America. We investigated the prevalence
