Báo cáo khoa học: "Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland | Virology Journal BioMed Central Open Access Molecular epidemiology of sexually transmitted human papillomavirus in a self referred group of women in Ireland John F Menton1 Suzanne M Cremin2 Lydie Canier1 Mary Horgan2 3 and Liam J Fanning 1 Address 1Molecular Virology Research and Diagnostic Laboratory Department of Medicine Cork University Hospital University College Cork Cork Ireland 2STI Clinic South Infirmary Victoria University Hospital Cork Ireland and 3Department of Infectious Disease Cork University Hospital Cork Ireland Email John F Menton - Suzanne M Cremin - Lydie Canier - Mary Horgan - Liam J Fanning - Corresponding author Published 23 July 2009 Received 5 June 2009 Accepted 23 July 2009 Virology Journal 2009 6 112 doi 1743-422X-6-112 This article is available from http content 6 1 1 12 2009 Menton et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Human papillomavirus HPV causes cervical cancer and external genital warts. The purpose of this study is to document the genotype distribution of HPV in females aged between 18 and 34 who self-referred to an STI clinic with visible external genital warts EGW . Scrapings were taken from visible external genital warts EGW . These scrapings were analysed by PCR for the presence of HPV DNA. Positive samples were then genotyped by means of a commercially available assay LiPA . A comparison of genotyping results determined by the LiPA assay and direct amplicon DNA sequencing was also performed. Results Ninety-two patients out of 105 samples 88 had detectable levels of HPV DNA. The majority of individuals with EGW 66 showed the .

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