Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An overview of molecular epidemiology of hepatitis B virus (HBV) in India | Virology Journal BioMed Central Open Access An overview of molecular epidemiology of hepatitis B virus HBV in India Sibnarayan Datta Address ICMR Virus Unit Kolkata Infectious Diseases Beleghata General Hospital Campus 57 Dr. Suresh Chandra Banerjee Road Kolkata 700010 India Email Sibnarayan Datta - sndatta1978@ Published 19 December 2008 Received 15 December 2008 Accepted 19 December 2008 Virologyjournal 2008 5 156 doi l743-422X-5-l56 This article is available from http content 5 l l56 2008 Datta licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Hepatitis B virus HBV is one of the major global public health problems. In India HBsAg prevalence among general population ranges from 2 to 8 placing India in intermediate HBV endemicity zone and the number of HBV carriers is estimated to be 50 million forming the second largest global pool of chronic HBV infections. India is a vast country comprised of multiracial communities with wide variations in ethnicity and cultural patterns which is attributable to its geographical location gene influx due to invasion and or anthropological migrations in the past. Moreover recent increase in trade trafficking and use of illicit drugs has also considerably influenced the epidemiology of HBV specifically in the eastern and north eastern parts of India. However data on the molecular epidemiology of HBV in India is scanty. HBV genotypes A and D have been well documented from different parts of mainland India. Interestingly in addition to genotypes A and D genotype C having high nucleotide similarity with south East Asian subgenotype Cs Cl strain have been detected exclusively from eastern Indian HBV carriers suggesting a recent introduction. Thus .
