Báo cáo khoa học: " Sales of oseltamivir in Norway prior to the emergence of oseltamivir resistant influenza A(H1N1) viruses in 2007–08"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sales of oseltamivir in Norway prior to the emergence of oseltamivir resistant influenza A(H1N1) viruses in 2007–08 | Virology Journal BioMed Central Open Access Short report Sales of oseltamivir in Norway prior to the emergence of oseltamivir resistant influenza A HINI viruses in 2007-08 Siri H Hauge 1 2 Hege S Blix3 Katrine Borgen1 Olav Hungnes4 Susanne G Dudman4 and Preben Aavitsland1 Address Department of Infectious Disease Epidemiology Norwegian Institute of Public Health PO Box 4404 Nydalen N-0403 Oslo Norway 2Norwegian Field Epidemiology Training Programme NorFETP Oslo Norway 3Department of Pharmacoepidemiology Norwegian Institute of Public Health PO Box 4404 Nydalen N-0403 Oslo Norway and 4Department of Virology Norwegian Institute of Public Health PO Box 4404 Nydalen N-0403 Oslo Norway Email Siri H Hauge - Hege S Blix - Katrine Borgen - Olav Hungnes - Susanne G Dudman - Preben Aavitsland - Corresponding author Published 12 May 2009 Virology Journal 2009 6 54 doi 1743-422X-6-54 Received 26 February 2009 Accepted 12 May 2009 This article is available from http content 6 1 54 2009 Hauge et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background An unprecedented high proportion of oseltamivir resistant influenza A H 1 N1 viruses emerged in the 2007-08 influenza season. In Norway two thirds of all tested A H1N1 viruses were resistant to the antiviral drug. In order to see if this emergence could be explained by a drug induced selection pressure we analysed data on the sales of oseltamivir in Norway for the years 2002-07. Methods We used data from two sources the Norwegian Drug Wholesales Statistics Database and the Norwegian Prescription Database .

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