ở trẻ em và thanh thiếu niên với bệnh viêm gan C. Hepatology 41: 1013 - 1018 Gonzalez-Peralta RP, Kelly DA, Haber B, Molleston J, Murray KF, Jonas MM, Shelton M, Mieli-Vergani G, Lurie Y, Martin S et al (2005) Interferon alfa-2b kết hợp với ribavirin cho điều trị bệnh viêm gan C mãn tính ở trẻ em: hiệu quả, an toàn, | 404 Patrick Gerner in children and adolescents with chronic hepatitis C. Hepatology 41 10131018 18 Gonzalez-Peralta RP Kelly DA Haber B Molleston J Murray KF Jonas MM Shelton M Mieli-Vergani G Lurie Y Martin S et al 2005 Interferon alfa-2b in combination with ribavirin for the treatment of chronic hepatitis C in children efficacy safety and pharmacokinetics. Hepatology 42 1010-1018 19 Ahn J Flamm S 2004 Peginterferon-alpha 2b and ribavirin. Expert Rev Anti Infect Ther 2 17-25 405 Pediatric Infectious Diseases Revisited ed. by Horst Schroten and Stefan Wirth 2007 Birkhauser Verlag Basel Switzerland Invasive fungal infections in children advances and perspectives Andreas H. Groll1 Julia Koehler2 and Thomas J. Walsh3 Infectious Disease Research Program Center for Bone Marrow Transplantation and Department of Pediatric Hematology Oncology University Children s Hospital Munster Germany 2Division of Infectious Diseases Children s Hospital Boston Boston Massachusetts USA 3Immunocompromised Host Section National Cancer Institute National Institutes of Health Bethesda Maryland USA Abstract Invasive fungal infections are important causes of morbidity and mortality in immunocompromised children. The past two decades have seen a dramatic increase in both number and overall relevance of invasive fungal infections in the hospital. At the same time however improved microbiological and imaging techniques together with an increased awareness have shifted the diagnosis of fungal infections from the autopsy theatre to the bedside. Major advances have been made in the definition of fungal diseases the algorithms of antifungal interventions the design and implementation of clinical trials and the development of standardized in vitro susceptibility testing. Most importantly however an array of new antifungal agents has entered the clinical arena and has made antifungal therapy more safe more effective but also more complicated. This article reviews some unique features of invasive .
