Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Is there a relationship between factor V Leiden and type 2 diabetes? | Journal of Translational Medicine BioMed Central Open Access Is there a relationship between factor V Leiden and type 2 diabetes Corrado Lodigiani 1 Paola Ferrazzi1 2 Pierpaolo Di Micco1 3 Luca Librè1 Stefano Genovese4 Ilaria Quaglia1 and Lidia Luciana Rota1 Address Thrombosis Center Istituto Clinico Humanitas IRCCS Rozzano MI Italy 2Unit of Laboratory and Clinical Chemistry Istituto Clinico Humanitas IRCCS Rozzano MI Italy 3Internal Medicine Fatebenefratelli Hospital of Naples Italy and 4Endocrine and Diabetes Unit Istituto Clinico Humanitas IRCCS Rozzano MI Italy Email Corrado Lodigiani - Paola Ferrazzi - Pierpaolo Di Micco - pdimicco@ Luca Librè - Stefano Genovese - Ilaria Quaglia - Lidia Luciana Rota - Corresponding author Published 26 June 2009 Received 19 March 2009 Journal of Translational Medicine 2009 7 52 doi l479-5876-7-52 Accepted 26 June 2009 This article is available from http content 7 1 52 2009 Lodigiani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Diabetes is well known risk factor for thrombotic events. The association between diabetes and venous thromboembolism is still matter of debate. However during diabetes an acquired thrombophilia is present and is due to the non-enzymatic glycosilation of clotting inhibitors as antithrombin thus leading to hypercoagulable state. A possibile relationship between the presence of FVL gene variant in type 1 or type 2 diabetes has been hypothysed by several reports in the Literature with non-univocal findings. Patients and methods .
