Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Comparison of the effects of vitamin D products in a psoriasis plaque test and a murine psoriasis xenograft model | Journal of Translational Medicine BioMed Central Open Access Comparison of the effects of vitamin D products in a psoriasis plaque test and a murine psoriasis xenograft model Peter H Kvist1 Lars Svensson1 Oskar Hagberg2 Vibeke Hoffmann3 Kaare Kemp1 and Mads A R0pke 4 Address Department of Disease Pharmacology LEO Pharma A S Industriparken 55 DK-2750 Ballerup Denmark 2Department of Biostatistics LEO Pharma A S Industriparken 55 DK-2750 Ballerup Denmark 3Department of Clinical Operations LEO Pharma A S Industriparken 55 DK-2750 Ballerup Denmark and 4Translational Research LEO Pharma A S Industriparken 55 DK-2750 Ballerup Denmark Email Peter H Kvist - phkv@ Lars Svensson - Oskar Hagberg - Vibeke Hoffmann - Kaare Kemp - Mads A R0pke - Corresponding author Published 17 December 2009 Received 8 September 2009 _ -T_AAAO J-IA I I o 11 A-ra r al 1 I AT Accepted 17 December 2009 Journal of Translational Medicine 2009 7 107 doi 186 1479-5876-7-107 This article is available from http content 7 1 107 2009 Kvist et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The aim of the present study was to compare the effects of Daivobet and calcipotriol on clinical score and biomarker responses in a modified version of the Scholtz-Dumas psoriasis plaque assay. Furthermore it was the aim to compare the effects of calcipotriol and betamethasone in the murine psoriasis xenograft model. Twenty four patients with psoriasis were treated topically once daily for three weeks whereas the grafted mice were treated for four weeks. Clinical .
