Báo cáo sinh học: " The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell | Virology Journal BioMed Central Research Open Access The simultaneous presence and expression of human hepatitis C virus HCV human herpesvirus-6 HHV-6 and human immunodeficiency virus-1 HIV-1 in a single human T-cell S Zaki Salahuddin 1 Katherine A Snyder1 2 Andre Godwin2 Renu Grewal1 John G Prichard3 Ann S Kelley4 and Dennis Revie2 Address Department of Basic Research California Institute of Molecular Medicine Ventura California USA 2Department of Biology California Lutheran University Thousand Oaks California USA 3Departments of Medicine and Family PracticeVentura County Medical Center Ventura CA and 4Department of Hematology and Oncology Ventura County Hematology-Oncology Specialists Ventura CA Email S Zaki Salahuddin - zaki@ Katherine A Snyder - ksnyder@ Andre Godwin - agodwin@ Renu Grewal - rtg602@ John G Prichard - johnprichard@ Ann S Kelley - annzaki@ Dennis Revie - revie@ Corresponding author Published 24 October 2007 Received 4 October 2007 Accepted 24 October 2007 Virology Journal 2007 4 106 doi 1743-422X-4-106 This article is available from http content 4 1 106 2007 Salahuddin et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract We have developed a system that isolates and replicates HCV in vitro. These isolates are called CIMM-HCV. This system has made it possible to analyze the biology nature and extent of HCV variability among other things. Individuals that are infected with HIV-1 are often also infected with HCV and HHV-6. In addition to HCV our lab has systems for replicating HIV-1 and HHV-6. We asked whether all these viruses could infect the same cells. We report here the successful infection of a

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