Báo cáo sinh học: " Evolution of temperate pathogens: the bacteriophage/bacteria paradigm"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Evolution of temperate pathogens: the bacteriophage/bacteria paradigm | Virology Journal BioMed Central Open Access Review Evolution of temperate pathogens the bacteriophage bacteria paradigm Arthur L Koch Address Biology Department Indiana University Bloomington IN 47405-6801 USA Email Arthur L Koch - koch@ Published 9 November 2007 Received 31 July 2007 Accepted 9 November 2007 Virology Journal 2007 4 121 doi 1743-422X-4-121 This article is available from http content 4 1 121 2007 Koch licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Taking as a pattern the T4 and lambda viruses interacting with each other and with their Gram-negative host Escherichia coli a general model is constructed for the evolution of gentle or temperate pathogens. This model is not simply either pure group or kin selection but probably is common in a variety of host-parasite pairs in various taxonomic groups. The proposed mechanism is that for its own benefit the pathogen evolved ways to protect its host from attack by other pathogens and this has incidentally protected the host. Although appropriate mechanisms would have been developed and excluded related viral species and also other quite different pathogens the important advance would have been when other individuals of the same species that arrive at the host subsequent to the first infecting one were excluded. Results Such a class of mechanisms would not compete one genotype with another but simply would be of benefit to the first pathogen that had attacked a host organism. Conclusion This would tend to protect and extend the life of the host against the detrimental effects of a secondarily infecting pathogen. This leads to the pathogens becoming more temperate via the now favorable co-evolution with its .

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