Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease | BioMed Central Health and Quality of Life Outcomes Open Access Short report Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease Monika R Asnani 1 Garth E Lipps2 and Marvin E Reid1 Address 1Sickle Cell Unit Tropical Medicine Research Institute University of the West Indies Mona Campus Kingston 7 Jamaica and 2Department of Psychology Sociology and Social Work University of the West Indies Mona Campus Kingston 7 Jamaica Email Monika RAsnani - Garth E Lipps - Marvin E Reid - Corresponding author Published 10 August 2009 Received 18 March 2009 Health and Quality of Life Outcomes 2009 7 75 doi 1477-7525-7-75 Accepted 10 August 2009 This article is available from http content 7 1 75 2009 Asnani et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Sickle cell disease is the commonest genetic disorder in Jamaica and most likely exerts numerous effects on quality of life QOL of those afflicted with it. The WHOQOL-Bref which is a commonly utilized generic measure of quality of life has never previously been utilized in this population. We have sought to study its utility in this disease population. Methods 491 patients with sickle cell disease were administered the questionnaire including demographics WHOQOL-Bref Short Form-36 SF-36 Flanagan s quality of life scale QOLS and measures of disease severity at their routine health maintenance visits to the sickle cell unit. Internal consistency reliabilities construct validity and known groups validity of the WHOQOL-Bref and its domains were examined and then compared to those of the other instruments. Results All three instruments had .
