Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Cultural adaptation into Spanish of the generalized anxiety disorder-7 (GAD-7) scale as a screening tool | García-Campayo et al. Health and Quality of Life Outcomes 2010 8 8 http content 8 1 8 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Cultural adaptation into Spanish of the generalized anxiety disorder-7 GAD-7 scale as a screening tool Javier García-Campayo1 2 Enric Zamorano3 Miguel A Ruiz4 5 Antonio Pardo4 5 María Pérez-Páramo6 Vanessa López-Gómez6 Olga Freire7 Javier Rejas7 Abstract Background Generalized anxiety disorder GAD is a prevalent mental health condition which is underestimated worldwide. This study carried out the cultural adaptation into Spanish of the 7-item self-administered GAD-7 scale which is used to identify probable patients with GAD. Methods The adaptation was performed by an expert panel using a conceptual equivalence process including forward and backward translations in duplicate. Content validity was assessed by interrater agreement. Criteria validity was explored using ROC curve analysis and sensitivity specificity predictive positive value and negative value for different cut-off values were determined. Concurrent validity was also explored using the HAM-A HADS and WHO-DAS-II scales. Results The study sample consisted of 212 subjects 106 patients with GAD with a mean age of years SD . Average completion time was 2 30 . No items of the scale were left blank. Floor and ceiling effects were negligible. No patients with GAD had to be assisted to fill in the questionnaire. The scale was shown to be onedimensional through factor analysis explained variance 72 . A cut-off point of 10 showed adequate values of sensitivity and specificity with AUC being statistically significant AUC p . The scale significantly correlated with HAM-A p HADS anxiety domain p and WHO-DAS II p . Limitations Elderly people particularly those very old may need some help to complete the scale. Conclusion After the cultural adaptation process a Spanish version of the GAD-7 .