Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Validation of a core outcome measure for palliative care in Africa: the APCA African Palliative Outcome Scale | Harding et al. Health and Quality of Life Outcomes 2010 8 10 http content 8 1 10 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Validation of a core outcome measure for palliative care in Africa the APCA African Palliative Outcome Scale Richard Harding1 Lucy Selman1 Godfrey Agupio2 Natalya Dinat3 Julia Downing4 Liz Gwyther5 Thandi Mashao6 1 I r- ft 1 U v n I J 13 I f IV I r I I 7 I I IV ỉ z i C rs L I I 1r 8 D nz L V D I Fz-sv ZI r 9 I vr r I I_I I z i z i I f f 1 Keletso Mmoiedi lony Moll Lydia Mpanga seouyira Barbara Panjatovic Irene J Higginson Abstract Background Despite the burden of progressive incurable disease in Africa there is almost no evidence on patient care or outcomes. A primary reason has been the lack of appropriate locally-validated outcome tools. This study aimed to validate a multidimensional scale the APCA African Palliative Outcome Scale in a multi-centred international study. Methods Validation was conducted across 5 African services and in 3 phases Phase 1. Face validity content analysis of qualitative interviews and cognitive interviewing of POS Phase 2. Construct validity correlation of POS with Missoula-Vitas Quality of Life Index Spearman s rank tests Phase 3. Internal consistency Cronbach s alpha calculated twice using 2 datasets test-retest reliability intraclass correlation coefficients calculated for 2 time points and time to complete calculated twice using 2 datasets . Results The validation involved 682 patients and 437 family carers interviewed in 8 different languages. Phase 1. Qualitative interviews N 90 patients N 38 carers showed POS items mapped well onto identified needs cognitive interviews N 73 patients N 29 carers demonstrated good interpretation Phase 2. POS-MVQoLI Spearman s rank correlations were low-moderate as expected N 285 Phase 3. N 307 2nd assessment mean hours after first SD Cronbach s Alpha was on both datasets indicating expected moderate internal consistency test-retest .
