Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Health-related Quality of Life in Vacuum-Assisted Breast Biopsy: short-term effects, long-term effects and predictors | Domeyer et al. Health and Quality of Life Outcomes 2010 8 11 http content 8 1 11 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Health-related Quality of Life in Vacuum-Assisted Breast Biopsy short-term effects long-term effects and predictors Philip J Domeyer Theodoros N Sergentanis Flora Zagouri George C Zografos Abstract Background The impact of Vacuum-assisted breast biopsy VABB 11-Gauge upon Health-related Quality of Life HRQoL remains an open field. This study aims to i assess short-term 4 days after VABB responses in terms of HRQoL after VABB ii evaluate long-term 18 months after VABB responses if any and iii examine whether these responses are modified by a variety of possible predictors anthropometric sociodemographic lifestyle habits breast-related parameters reproductive history VABB-related features and complications seasonality . Methods This study included 102 eligible patients undergoing VABB and having benign lesions. A variable number of cores 24-96 cores has been excised. HRQoL was assessed by EQ-5D and SF-36 questionnaires i in the morning of the VABB procedure day baseline measurement ii four days after VABB early post-biopsy measurement and iii 18 months after VABB late post-biopsy measurement . Statistical analysis comprised two steps i. evaluation of differences in EQ-5D SF-36 dimensions and calculated scores baseline versus early postbiopsy measurement and baseline versus late post-biopsy measurement and ii. assessment of predictors through multivariate linear logistic ordinal logistic regression as appropriate. Results At baseline patients presented with considerable anxiety EQ-5D anxiety depression dimension EQ-5D TTO VAS indices SF-36 Mental Health dimension . At the early post-biopsy measurement women exhibited deterioration in Usual Activities EQ-5D and Role Functioning-Physical dimensions. At the late measurement women exhibited pain EQ-5D pain discomfort and SF-36 Bodily Pain deterioration in Physical .
