Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Self-reported physical and mental health status and quality of life in adolescents: a latent variable mediation model | Sawatzky et al. Health and Quality of Life Outcomes 2010 8 17 http content 8 1 17 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Self-reported physical and mental health status and quality of life in adolescents a latent variable mediation model Richard Sawatzky1 Pamela A Ratner2 Joy L Johnson2 Jacek A Kopec3 Bruno D Zumbo4 Abstract Background We examined adolescents differentiation of their self-reported physical and mental health status the relative importance of these variables and five important life domains satisfaction with family friends living environment school and self with respect to adolescents global quality of life QOL and the extent to which the five life domains mediate the relationships between self-reported physical and mental health status and global QOL. Methods The data were obtained via a cross-sectional health survey of 8 225 adolescents in 49 schools in British Columbia Canada. Structural equation modeling was applied to test the implied latent variable mediation model. The Pratt index d was used to evaluate variable importance. Results Relative to one another self-reported mental health status was found to be more strongly associated with depressive symptoms and self-reported physical health status more strongly associated with physical activity. Selfreported physical and mental health status and the five life domains explained 76 of the variance in global QOL. Relatively poorer mental health and physical health were significantly associated with lower satisfaction in each of the life domains. Global QOL was predominantly explained by three of the variables mental health status d 30 satisfaction with self d 42 and satisfaction with family d 20 . Satisfaction with self and family were the predominant mediators of mental health and global QOL 45 total mediation and of physical health and global QOL 68 total mediation . Conclusions This study provides support for the validity and relevance of differentiating .