Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Quality of life among adolescents with sickle cell disease: mediation of pain by internalizing symptoms and parenting stress | BioMed Central Health and Quality of Life Outcomes Research Quality of life among adolescents with sickle cell disease mediation of pain by internalizing symptoms and parenting stress Lamia P Barakat 1 Chavis A Patterson2 Lauren C Daniel1 and Carlton Dampier2 Open Access Address Department of Psychology Drexel University Philadelphia Pennsylvania USA and 2Marian Anderson Comprehensive Sickle Cell Center of St. Christopher s Hospital for Children and Department of Pediatrics Drexel University College of Medicine Philadelphia Pennsylvania USA Email Lamia P Barakat - Chavis A Patterson - lcd34@ Lauren C Daniel - Carlton Dampier - CDampie@ Corresponding author Published 9 August 2008 Received 13 December 2007 Health and Quality of Life Outcomes 2008 6 60 doi 1477-7525-6-60 Accepted 9 August 2008 This article is available from http content 6 1 60 2008 Barakat et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background This study aimed to clarify associations between pain psychological adjustment and family functioning with health-related quality of life HRQOL in a sample of adolescents with sickle cell disease SCD utilizing teen- and parent-report. Methods Forty-two adolescents between the ages of 12 and 18 with SCD and their primary caregivers completed paper-and-pencil measures of pain teen s psychological adjustment and HRQOL. In addition primary caregivers completed a measure of disease-related parenting stress. Medical file review established disease severity. Results Pearson correlations identified significant inverse .
