Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài : Responsiveness of the EQ-5D in breast cancer patients in their first year after treatment | Health and Quality of Life Outcomes BioMed Central Open Access Responsiveness of the EQ-5D in breast cancer patients in their first year after treatment Merel L Kimman 1 2 Carmen D Dirksen3 Philippe Lambin1 2 and Liesbeth J Boersma1 2 Address 1MAASTRO Clinic School for Oncology and Developmental Biology GROW Maastricht University Medical Centre Maastricht the Netherlands 2Department of Radiation Oncology MAASTRO Maastricht University Medical Centre Maastricht the Netherlands and 3Department of Clinical Epidemiology and Medical Technology Assessment Maastricht University Medical Centre Maastricht the Netherlands Email Merel L Kimman - Carmen D Dirksen - Philippe Lambin - Liesbeth J Boersma - Corresponding author Published 7 February 2009 Received 4 November 2008 Health and Quality of Life Outcomes 2009 7 11 doi 1477-7525-7-11 Accepted 7 February 2009 This article is available from http content 7 1 1 1 2009 Kimman et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background aim The EQ-5D is a generic health-related quality of life HRQoL measure that is used for the purpose of economic evaluations of health interventions. Therefore it has to be responsive to meaningful changes in health in the patient population under investigation. The aim of this study was to investigate the responsiveness of the EQ-5D in breast cancer patients in their first year after treatment. Methods The subscale global health of the disease-specific HRQoL measure EORTC QLQ-C30 was used as a reference instrument to determine meaningful changes in health and identify subgroups of patients patients reporting a moderate-large .
