Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Genetic variability of the envelope gene of Type D simian retrovirus-2 (SRV-2) subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species | BioMed Central Virology Journal Research Open Access Genetic variability of the envelope gene of Type D simian retrovirus-2 SRV-2 subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species Jeannette Philipp-Staheli1 Taya Marquardt1 Margaret E Thouless1 A Gregory Bruce Richard F Grant2 Che-Chung Tsai2 and Timothy M Rose 1 Address Department of Pathobiology School of Public Health and Community Medicine University of Washington Seattle Washington USA and Washington National Primate Research Center University of Washington Seattle Washington USA Email Jeannette Philipp-Staheli - jstaheli@ Taya Marquardt - taya@ Margaret E Thouless - methoul@ A Gregory Bruce - bruceg@ Richard F Grant - Rgrant@ Che-Chung Tsai - cctsai@ Timothy M Rose - trose@ Corresponding author Published 06 March 2006 Received 26 October 2005 Accepted 06 March 2006 VirologyJournal2006 3 11 doi l743-422X-3-11 This article is available from http content 3 1 1 1 2006Philipp-Staheli et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background D-type simian retrovirus-2 SRV-2 causes an AIDS-like immune deficiency syndrome SAIDS in various macaque species. SAIDS is often accompanied by retroperitoneal fibromatosis RF an aggressive fibroproliferative disorder reminiscent of Kaposi s sarcoma in patients with HIV-induced AIDS. In order to determine the association of SRV-2 subtypes with SAIDS-RF and study the evolution and transmission of SRV-2 in captive macaque populations we have molecularly characterized the env gene of a number of SRV-2 isolates from different .
