Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Objective assessment of motor fatigue in multiple sclerosis using kinematic gait analysis: a pilot study | Sehle et al. Journal of NeuroEngineering and Rehabilitation 2011 8 59 http content 8 1 59 Iril JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Objective assessment of motor fatigue in multiple sclerosis using kinematic gait analysis a pilot study A I I cv L c A rM 11 I S-. V 1 2 I 1 I I c X u- V r f 3 0 I KỲ fs C- xil r3 o r r A f V4 A k r t- I Ch m r vr 5 nn I Aida Seme Annegret Iviundermann Klaus Starrost Simon Sailer Inna Becher Christian Dettmers ano Manfred Vieten1 Abstract Background Fatigue is a frequent and serious symptom in patients with Multiple Sclerosis MS . However to date there are only few methods for the objective assessment of fatigue. The aim of this study was to develop a method for the objective assessment of motor fatigue using kinematic gait analysis based on treadmill walking and an infrared-guided system. Patients and methods Fourteen patients with clinically definite MS participated in this study. Fatigue was defined according to the Fatigue Scale for Motor and Cognition FSMC . Patients underwent a physical exertion test involving walking at their pre-determined patient-specific preferred walking speed until they reached complete exhaustion. Gait was recorded using a video camera a three line-scanning camera system with 11 infrared sensors. Step length width and height maximum circumduction with the right and left leg maximum knee flexion angle of the right and left leg and trunk sway were measured and compared using paired t-tests a . In addition variability in these parameters during one-minute intervals was examined. The fatigue index was defined as the number of significant mean and SD changes from the beginning to the end of the exertion test relative to the total number of gait kinematic parameters. Results Clearly for some patients the mean gait parameters were more affected than the variability of their movements while other patients had smaller differences in mean gait .