Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Quantifying the quality of hand movement in stroke patients through three-dimensional curvature | Osu et al. Journal of NeuroEngineering and Rehabilitation 2011 8 62 http content 8 1 62 Iril JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Quantifying the quality of hand movement in stroke patients through three-dimensional curvature 1 t 2t 2 1 2 Rieko Osu Kazuko Ota Toshiyuki Fujiwara Yohei Otaka Mitsuo Kawato and Meigen Liu Abstract Background To more accurately evaluate rehabilitation outcomes in stroke patients movement irregularities should be quantified. Previous work in stroke patients has revealed a reduction in the trajectory smoothness and segmentation of continuous movements. Clinically the Stroke Impairment Assessment Set SIAS evaluates the clumsiness of arm movements using an ordinal scale based on the examiner s observations. In this study we focused on three-dimensional curvature of hand trajectory to quantify movement and aimed to establish a novel measurement that is independent of movement duration. We compared the proposed measurement with the SIAS score and the jerk measure representing temporal smoothness. Methods Sixteen stroke patients with SIAS upper limb proximal motor function Knee-Mouth test scores ranging from 2 incomplete performance to 4 mild clumsiness were recruited. Nine healthy participant with a SIAS score of 5 normal also participated. Participants were asked to grasp a plastic glass and repetitively move it from the lap to the mouth and back at a conformable speed for 30 s during which the hand movement was measured using OPTOTRAK. The position data was numerically differentiated and the three-dimensional curvature was computed. To compare against a previously proposed measure the mean squared jerk normalized by its minimum value was computed. Age-matched healthy participants were instructed to move the glass at three different movement speeds. Results There was an inverse relationship between the curvature of the movement trajectory and the patient s SIAS score. The median .