Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: An explorative, cross-sectional study into abnormal muscular coupling during reach in chronic stroke patients | Prange et al. Journal of NeuroEngineering and Rehabilitation 2010 7 14 http content 7 1 14 l dl JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access An explorative cross-sectional study into abnormal muscular coupling during reach in chronic stroke patients Gerdienke B Prange 1 Michiel JA Jannink1 2 Arno HA Stienen2 3 Herman van der Kooij2 4 Maarten J IJzerman5 Hermie J Hermens1 6 Abstract Background In many stroke patients arm function is limited which can be related to an abnormal coupling between shoulder and elbow joints. The extent to which this can be translated to activities of daily life ADL in terms of muscle activation during ADL-like movements is rather unknown. Therefore the present study examined the occurrence of abnormal coupling on functional ADL-like reaching movements of chronic stroke patients by comparison with healthy persons. Methods Upward multi-joint reaching movements 20 repetitions at a self-selected speed to resemble ADL were compared in two conditions once facilitated by arm weight compensation and once resisted to provoke a potential abnormal coupling. Changes in movement performance joint angles and muscle activation amplitude of activity and co-activation between conditions were compared between healthy persons and stroke patients using a repeated measures ANOVA. Results The present study showed slight changes in joint excursion and muscle activation of stroke patients due to shoulder elevation resistance during functional reach. Remarkably in healthy persons similar changes were observed. Even the results of a sub-group of the more impaired stroke patients did not point to an abnormal coupling between shoulder elevation and elbow flexion during functional reach. Conclusions The present findings suggest that in mildly and moderately affected chronic stroke patients ADL-like arm movements are not substantially affected by abnormal synergistic coupling. In this case it is implied that other .