Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : New views on the hypothesis of respiratory cancer risk from soluble nickel exposure; and reconsideration of this risk's historical sources in nickel refineries | Journal of Occupational Medicine and Toxicology BioMed Central Open Access New views on the hypothesis of respiratory cancer risk from soluble nickel exposure and reconsideration of this risk s historical sources in nickel refineries James G Heller 1 2 Philip G Thornhill13 and Bruce R Conard14 5 Address 1James G. Heller Consulting Inc. 1 Berney Crescent Toronto ON M4G 3G4 Canada 2Dalla Lana School of Public Health University of Toronto 6th Floor Health Sciences Building 155 College Street Toronto ON M5T 3M7 Canada Metallurgical Research Falconbridge Ltd Toronto ON Canada 4Environmental and Health Sciences Inco Ltd Toronto ON Canada and 5BR Conard Consulting Inc. 153 Balsam Drive Oakville ON L6J 3X4 Canada Email James G Heller - jgheller@ Philip G Thornhill - info@ Bruce R Conard - bconard@ Corresponding author fEqual contributors Published 23 August 2009 Received 5 March 2009 Journal of Occupational Medicine and Toxicology 2009 4 23 doi 86 1745-6673-4-23 Accepted 23 August 2009 This article is available from http content 4 1 23 2009 Heller et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction While epidemiological methods have grown in sophistication during the 20th century their application in historical occupational and environmental health research has also led to a corresponding growth in uncertainty in the validity and reliability of the attribution of risk in the resulting studies particularly where study periods extend back in time to the immediate postwar era 1945-70 when exposure measurements were sporadic unsystematically collected and primitive in technique and more so to the pre-WWII era when exposure data were essentially .
