Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : The role of tendon microcirculation in Achilles and patellar tendinopathy | Journal of Orthopaedic Surgery and Research BioMed Central Open Access The role of tendon microcirculation in Achilles and patellar tendinopathy Karsten Knobloch Address Plastic Hand and reconstructive surgery Hannover Medical School Germany Email Karsten Knobloch - kknobi@ Published 30 April 2008 Received 8 June 2007 Journal of Orthopaedic Surgery and Research 2008 3 18 doi 1749-799X-3-18 Accepted 30 April 2008 This article is available from http content 3 1 18 2008 Knobloch licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Tendinopathy is of distinct interest as it describes a painful tendon disease with local tenderness swelling and pain associated with sonographic features such as hypoechogenic texture and diameter enlargement. Recent research elucidated microcirculatory changes in tendinopathy using laser Doppler flowmetry and spectrophotometry such as at the Achilles tendon the patellar tendon as well as at the elbow and the wrist level. Tendon capillary blood flow is increased at the point of pain. Tendon oxygen saturation as well as tendon postcapillary venous filling pressures determined non-invasively using combined Laser Doppler flowmetry and spectrophotometry can quantify in real-time how tendon microcirculation changes over with pathology or in response to a given therapy. Tendon oxygen saturation can be increased by repetitive intermittent short-term ice applications in Achilles tendons this corresponds to ischemic preconditioning a method used to train tissue to sustain ischemic damage. On the other hand decreasing tendon oxygenation may reflect local acidosis and deteriorating tendon metabolism. Painful eccentric training a common therapy for Achilles patellar .