Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique | Journal of Orthopaedic Surgery and Research BioMed Central Research article Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique Jian P Wu 1 Thomas B Kirk1 and Ming H Zheng2 Open Access Address 13D imaging laboratory the School of Mechanical Engineering The University of Western Australia Perth WA Australia and 2Orthopaedic Surgery School of Surgery and Pathology The University of Western Australia Perth WA Australia Email Jian P Wu - wping@ Thomas B Kirk - kirk@ Ming H Zheng - Corresponding author Published 17 July 2008 Received 24 August 2007 Journal of Orthopaedic Surgery and Research 2008 3 29 doi 1749-799X-3-29 Accepted I7 July 2008 This article is available from http content 3 1 29 2008 Wu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction The collagen structure in the superficial zone of articular cartilage is critical to the tissue s durability. Early osteoarthritis is often characterized with fissures on the articular surface. This is closely related to the disruption of the collagen network. However the traditional histology can not offer visualization of the collagen structure in articular cartilage because it uses conventional optical microscopy that does not have insufficient imaging resolution to resolve collagen from proteoglycans in hyaline articular cartilage. This study examines the 3D collagen network of articular cartilage scored from 0 to 2 in the scoring system of International Cartilage Repair Society and aims .
