Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Sevoflurane requirement during elective ankle day surgery: the effects of etirocoxib premedication, a prospective randomised study | Journal of Orthopaedic Surgery and Research BioMed Central Research article Sevoflurane requirement during elective ankle day surgery the effects of etirocoxib premedication a prospective randomised study Ibrahim Turan1 Anette Hein2 Eva Jacobson1 and Jan G Jakobsson 3 Address 1Karolinska Institutet Foot Ankle Surgical Centre Stockholm Sweden 2Karolinska Institutet Department of Anaesthesia Danderyd Hospital Stockholm Sweden and 3Karolinska Institutet Institution for Physiology Pharmacology Department of Anaesthesia Intensive Care Foot Ankle Surgical Centre Stockholm Sweden Email Ibrahim Turan - Anette Hein - Eva Jacobson - Jan G Jakobsson - Corresponding author Open Access Published II September 2008 Received 8 April 2008 Journal of Orthopaedic Surgery and Research 2008 3 40 doi 1749-799X-3-40 Accepted 11 September 2008 This article is available from http content 3 1 40 2008 Turan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Anti-inflammatory drugs NSAIDs have become an important part of the pain management in day surgery. The aim of the present study was to evaluate the effect of Coxib premedication on the intra-operative anaesthetic requirements in patients undergoing elective ankle surgery in general anaesthesia. Type of study Prospective randomized study of the intra-operative anaesthetic-sparing effects of etoricoxib premedication as compared to no NSAID preoperatively. Methods The intra-operative requirement of sevoflurane was studied in forty-four ASA 1-2 patients undergoing elective ankle day .