Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Pre-surgical radiologic identification of peri-prosthetic osteolytic lesions around TKRs: a pre-clinical investigation of diagnostic accuracy | Journal of Orthopaedic Surgery and Research BioMed Central Open Access Pre-surgical radiologic identification of peri-prosthetic osteolytic lesions around TKRs a pre-clinical investigation of diagnostic accuracy Timothy P Kurmis 1 Andrew P Kurmis2 David G Campbell3 and John P Slavotinek4 Address Department of Orthopaedic Surgery Flinders Medical Centre Bedford Park South Australia Australia 2School of Medicine Flinders University Bedford Park South Australia Australia 3Wakefield Orthopaedic Clinic Adelaide South Australia Australia and 4Division of Medical Imaging Flinders Medical Centre Bedford Park South Australia Australia Email Timothy P Kurmis - Andrew P Kurmis - David G Campbell - hipknee@ John P Slavotinek - Corresponding author Published 3 October 2008 Received 12 March 2008 Journal of Orthopaedic Surgery and Research 2008 3 47 doi l749-799X-3-47 Accepted 3 October 2008 This article is available from http content 3 1 47 2008 Kurmis et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Emerging longitudinal data appear to demonstrate an alarming trend towards an increasing prevalence of osteolysis-induced mechanical failure following total knee replacement TKR . Even with high-quality multi-plane X-rays accurate pre-surgical evaluation of osteolytic lesions is often difficult. This is likely to have an impact on surgical management and provides reasonable indication for the development of a model allowing more reliable lesion assessment. The aim of this study using a simulated cadaver model was to explore the accuracy of rapid spiral computed tomography CT examination in the .