Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Modular endoprosthetic replacement for metastatic tumours of the proximal femur | Journal of Orthopaedic Surgery and Research BioMed Central Open Access Research article Modular endoprosthetic replacement for metastatic tumours of the proximal femur Coonoor R Chandrasekar Robert J Grimer Simon R Carter Roger M Tillman and Adesegun T Abudu Address Royal Orthopaedic Hospital Birmingham UK Email Coonoor R Chandrasekar - crc12@ Robert J Grimer - Simon R Carter - Roger M Tillman - Adesegun T Abudu - Corresponding author Published 4 November 2008 Received 14 June 2008 Journal of Orthopaedic Surgery and Research 2008 3 50 doi l749-799X-3-50 Accepted 4 November 2008 This article is available from http content 3 1 50 2008 Chandrasekar et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background and aims Endoprosthetic replacements of the proximal femur are commonly required to treat destructive metastases with either impending or actual pathological fractures at this site. Modular prostheses provide an off the shelf availability and can be adapted to most reconstructive situations for proximal femoral replacements. The aim of this study was to assess the clinical and functional outcomes following modular tumour prosthesis reconstruction of the proximal femur in 100 consecutive patients with metastatic tumours and to compare them with the published results of patients with modular and custom made endoprosthetic replacements. Methods 100 consecutive patients who underwent modular tumour prosthetic reconstruction of the proximal femur for metastases using the METS system from 200 1 to 2007 were studied. The patient tumour and treatment factors in relation to overall .