Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Therapeutic immunisation of rabbits with cottontail rabbit papillomavirus (CRPV) virus-like particles (VLP) induces regression of established papillomas | Virology Journal BioMed Central Open Access Short report Therapeutic immunisation of rabbits with cottontail rabbit papillomavirus CRPV virus-like particles VLP induces regression of established papillomas Vandana A Govan 1 Edward P Rybicki1 2 and Anna-Lise Williamson1 3 Address 1Institute of Infectious Disease and Molecular Medicine Faculty of Health Sciences University of Cape Town Observatory Cape Town South Africa 2Department of Molecular Cell Biology University of Cape Town Observatory Cape Town South Africa and 3National Health Laboratory Service Groote Schuur Hospital Observatory Cape Town South Africa Email Vandana A Govan - Edward P Rybicki - Anna-Lise Williamson - Corresponding author Published 20 March 2008 Received 14 February 2008 Accepted 20 March 2008 Virology Journal 2008 5 45 doi l 743-422X-5-45 This article is available from http content 5 1 45 2008 Govan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract There is overwhelming evidence that persistent infection with high-risk human papillomaviruses HR-HPV is the main risk factor for invasive cancer of the cervix. Due to this global public health burden two prophylactic HPV L1 virus-like particles VLP vaccines have been developed. While these vaccines have demonstrated excellent type-specific prevention of infection by the homologous vaccine types high and low risk HPV types no data have been reported on the therapeutic effects in people already infected with the low-risk HPV type. In this study we explored whether regression of CRPV-induced papillomas could be .
