Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Comparative analysis of full genomic sequences among different genotypes of dengue virus type 3 | BioMed Central Virology Journal Research Comparative analysis of full genomic sequences among different genotypes of dengue virus type 3 Chwan-Chuen King1 Day-Yu Chao 2 Li-Jung Chien3 Gwong-Jen J Chang4 Ting-Hsiang Lin3 Yin-Chang Wu3 and Jyh-Hsiung Huang3 Address institute of Epidemiology College of Public Health National Taiwan University Taipei Taiwan 10020 PRoC institute of Veterinary Public Health College of Veterinary National Chung-Shin University Taipei Taiwan 402 PRoC 3Center for Disease Control Department of Health Taipei Taiwan 100 PRoC and 4Division of Vector-Borne Infectious Diseases National Center for Infectious Diseases Centers for Disease Control and Prevention CDC Fort Collins Colorado 80521 USA Email Chwan-Chuen King - cc_king99@ Day-Yu Chao - dychao@ Li-Jung Chien - Chien@ Gwong-Jen J Chang - gxc7@ Ting-Hsiang Lin - thlin@ Yin-Chang Wu - ycw@ Jyh-Hsiung Huang - jhh@ Corresponding author Open Access Published 21 May 2008 Received 28 January 2008 Accepted 21 May 2008 Virology journal 2008 5 63 doi l743-422X-5-63 This article is available from http content 5 1 63 2008 King et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Although the previous study demonstrated the envelope protein of dengue viruses is under purifying selection pressure little is known about the genetic differences of full-length viral genomes of DENV-3. In our study complete genomic sequencing of DENV-3 strains collected from different geographical locations and isolation years were determined and the sequence diversity as well as selection .