Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Oocyte-granulosa-theca cell interactions during preantral follicular development | Journal of Ovarian Research BioMed Central Open Access Oocyte-granulosa-theca cell interactions during preantral follicular development Makoto Orisaka 1 Kimihisa Tajima1 Benjamin K Tsang2 3 4 5 and Fumikazu Kotsuji1 Address Department of Obstetrics Gynecology University of Fukui Matsuoka Fukui 910-1193 Japan Reproductive Biology Unit and Division of Reproductive Medicine Department of Obstetrics University of Ottawa Ontario Canada 3Gynaecology and Cellular Molecular Medicine University of Ottawa Ontario Canada 4Chronic Disease Program Ottawa Hospital Research Institute The Ottawa Hospital Civic Campus Ottawa Ontario K1Y 4E9 Canada and 5World Class University Major in Biomodulation Department of Agricultural Biotechnology College of Agriculture and Life Sciences Seoul National University South Seoul 151-921 South Korea Email Makoto Orisaka - orisaka@ KimihisaTajima - kimihisa@ Benjamin K Tsang - btsang@ Fumikazu Kotsuji - kotsujif@ Corresponding author Published 9 July 2009 Received 27 May 2009 Journal of Ovarian Research 2009 2 9 doi 1757-2215-2-9 Accepted 9 July 2009 This article is available from http content 2 1 9 2009 Orisaka et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract The preantral-early antral follicle transition is the penultimate stage of follicular development in terms of gonadotropin dependence and follicle destiny growth versus atresia . Follicular growth during this period is tightly regulated by oocyte-granulosa-theca cell interactions. Formation of the theca cell layer is a key event that occurs during this transitional stage. Granulosal factor s stimulates the recruitment of theca cells from cortical stromal
