Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Struma ovarii associated with pseudo-Meigs’ syndrome and elevated serum CA 125: a case report and review of the literature | Jiang et al. Journal of Ovarian Research 2010 3 18 http content 3 1 18 JOURNAL OF OVARIAN RESEARCH CASE REPORT Open Access Struma ovarii associated with pseudo-Meigs syndrome and elevated serum CA 125 a case report and review of the literature Wei Jiang Xin Lu Zhi Ling Zhu Xi Shi Liu Cong Jian Xu Abstract The association of pseudo-Meigs syndrome elevation of CA 125 to the struma ovarii is a rare condition. So far only nine cases have been reported in English literature through MEDLINE search. Here we report a 46-year-old case of the struma ovarii presented with ascites hydrothorax right ovarian mass and elevated serum CA 125 level. These findings were misdiagnosed for an ovarian malignancy at the first impression. Immediate resolution of the ascites hydrothorax and normalization of the serum CA 125 level were followed by ovarian mass removal. Struma ovarii could be a rare cause of ascites hydrothorax ovarian mass and elevated CA 125. This rare condition should be considered in the differential diagnosis in patents with ascites and pleural effusions but with negative cytology. Background Struma ovarii is a rare ovarian neoplasm derived from germ cells in a mature teratoma. This tumor is generally benign although malignant transformation has been reported 1 . The preoperative diagnosis is generally difficult. Thyroid hormones may be produced and in a few cases asymptomatic women may develop definitive clinical hypothyroidism after resection of struma ovarii. We here report an unusual case of a 46-year-old woman presented with ascites right ovarian mass and elevated CA 125 level which was suspicious for an ovarian malignancy and underwent a total hysterectomy and bilateral salpingo-oophorectomy. The pathologic diagnosis was struma ovarii a specialized ovarian teratoma composed predominantly of mature thyroid tissue. The postoperative period was uneventful and her thyroid function was normal. We had reviewed the related literatures in this .
