báo cáo hóa học:" A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espírito Santo, Brazil | Paes et al. Journal of Ovarian Research 2011 4 14 http content 4 1 14 RESEARCH JOURNAL OF OVARIAN RESEARCH Open Access A retrospective analysis of clinicopathological and prognostic characteristics of ovarian tumors in the State of Espirito Santo Brazil 1 1 1 1 1 Marcela F Paes Renata D Daltoé Klesia P Madeira Lucas CD Rezende Gabriela M Sirtoli Alice L Herlinger 3 2 11 14 Leticia S Souza Luciana B Coitinho Débora Silva Murilo F Cerri Ana Cristina N Chiaradia Alex A Carvalho Ian V Silva3 and Leticia BA Rangel1 Abstract Background Ovarian cancer is sixth most common cancer among women and the leading cause of death in women with gynecological malignancies. Despite the great impact ovarian cancer has on women s health and its great impact in public economy Brazil still lacks valuable information concerning epidemiological aspects of this disease Methods We ve compiled clinical data of all ovarian tumors registered at the two public hospitals of reference 1997 - 2007 such as patients age at diagnosis tumor histological type tumor stage chemotherapy regimens chemotherapy responsiveness disease-free survival and overall survival. Results Women s mean age at diagnosis was for ovarian cancer for borderline tumors and for adenomas. Among epithelial ovarian cancer cases were of serous were of mucinous and were of endometrioid type exceptionally serous carcinoma was diagnosed in women younger than 30 years old. Endometrioid cancer had lower disease-free survival than others p . Cases were predominantly diagnosed as poor prognosis disease FIGO III and IV . Regarding responsiveness to platinumbased therapy of patients were resistant whereas susceptible. From these we found equally responsiveness to platinum alone or its association with paclitaxel or cyclophosphamide. Discussion Our data agreed with other studies regarding mean patients age at diagnosis histological type .

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