Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Disease Progression Among Untreated HIV-Infected Patients in South Ethiopia: Implications for Patient Care | Journal of the International AIDS Society BioMed Central Research article Disease Progression Among Untreated HIV-Infected Patients in South Ethiopia Implications for Patient Care Degu Jerene 1 and Bernt Lindtjorn2 Address 1HIV AIDS Coordinator Arba Minch Hospital Arba Minch Ethiopia PhD Candidate Centre for International Health University of Bergen Bergen Norway and 2Professor Centre for International Health University of Bergen Bergen Norway Email Degu Jerene - Corresponding author Open Access Published 30 August 2005 Journal of the International AIDS Society 2005 7 66 This article is available from http content 7 3 66 Abstract Context The natural course of HIV disease progression among resource-poor patient populations has not been clearly defined. Objective To describe predictors of HIV disease progression as seen at an outpatient clinic in a resource-limited setting in rural Ethiopia. Design This prospective cohort study included all adult HIV patients who visited an outpatient clinic at Arba Minch hospital in South Ethiopia between January 30 2003 and April I 2004. Clinical and hematologic measurements were done at baseline and every I2 weeks thereafter until the patient was transferred put on antiretroviral therapy was lost to follow-up or died. Community agents reported patient status every month. Setting A district hospital with basic facilities for HIV testing and patient monitoring. Main Outcome Measures Death diagnosis of tuberculosis and change in disease stage. Results We followed 207 patients for a median duration of I9 weeks range 060 weeks . A total of I32 64 of them were in WHO stage III. The overall mortality rate was 46 per I00 person-years of observation PYO . Mortality increased with advancing disease stage. Diarrhea oral thrush and low total lymphocyte count were significant markers of mortality. The incidence of
