Health and Quality of Life Outcomes BioMed Central Research Open Access Medication Use by Persons with Chronic Fatigue Syndrome: Results of a Randomized Telephone Survey in Wichita, Kansas James F Jones*, Rosane Nisenbaum and William C Reeves Address: Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop A15, Atlanta, GA 30333 Email: James F Jones* - jaj9@; Rosane Nisenbaum - ran7@; William C Reeves - wcr1@ * Corresponding author Published: 02 December 2003 Health and Quality of Life Outcomes 2003, 1:74 This article is available from: Received: 08 October 2003 Accepted: 02 December 2003 ©. | BioMed Central Health and Quality of Life Outcomes Research Open Access Medication Use by Persons with Chronic Fatigue Syndrome Results of a Randomized Telephone Survey in Wichita Kansas James F Jones Rosane Nisenbaum and William C Reeves Address Division of Viral and Rickettsial Diseases National Center for Infectious Diseases Centers for Disease Control and Prevention 1600 Clifton Road Mail Stop A15 Atlanta GA 30333 Email James F Jones - jaj9@ Rosane Nisenbaum - ran7@ William C Reeves - wcr1@ Corresponding author Published 02 December 2003 Received 08 October 2003 Accepted 02 December 2003 Health and Quality of Life Outcomes 2003 1 74 r This article is available from http content 1 1 74 2003 Jones et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background Chronic fatigue syndrome CFS is characterized by profound fatigue which substantially interferes with daily activities and a characteristic symptom complex. Patients use a variety of prescribed and self-administered medications vitamins and supplements for relief of their symptoms. The objective of this study was to describe utilization of medications and supplements by persons with CFS and non-fatigued individuals representative of the general population of Wichita Kansas. Methods We used a random-digit dialing telephone survey to identify persons with CFS in the general population of Wichita Kansas. Subjects who on the basis of telephone interview met the CFS case definition and randomly selected non-fatigued controls were invited for a clinic evaluation that included self-reported use of medications and supplements. Sex-adjusted odds ratios and 95 confidence interval were estimated to measure the association between CFS and use of various drug categories. Results We clinically .