Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Psychosocial and socioeconomic burden of vasomotor symptoms in menopause: A comprehensive review | BioMed Central Health and Quality of Life Outcomes Review Open Access Psychosocial and socioeconomic burden of vasomotor symptoms in menopause A comprehensive review Wulf H Utian Address North American Menopause Society 5900 Lander Brook Drive Mayfield Heights OH 44124 USA Email Wulf H Utian - utian@ Corresponding author Published 05 August 2005 Received 22 June 2005 Health and Quality of Life Outcomes 2005 3 47 doi 1477-7525-3- Accepted 05 August 2005 47 This article is available from http content 3 1 47 2005 Utian licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Many women experience vasomotor symptoms at or around the time of menopause. Hot flushes and night sweats are considered primary menopausal symptoms that may also be associated with sleep and mood disturbances as well as decreased cognitive function. All of these symptoms may lead to social impairment and work-related difficulties that significantly decrease overall quality of life. Hot flushes have shown a great deal of variability in their frequency and severity in women. In some women hot flushes persist for several months in others they may last for more than 10 years. Traditionally vasomotor symptoms were reported to begin 5 to 10 years prior to the cessation of the final menstrual cycle corresponding with the initial decline in circulating gonadal hormones however night sweats in particular most often begin in perimenopause. The pathogenesis of hot flushes has not yet been fully elucidated but the circuitry involving estrogen and neurotransmitters norepinephrine and serotonin specifically are hypothesized to play a major role in the altered homeostatic thermoregulatory mechanisms underlying these events. .
