Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Development and validation of a quality of life questionnaire for patients with colostomy or ileostomy | BioMed Central Health and Quality of Life Outcomes Research Open Access Development and validation of a quality of life questionnaire for patients with colostomy or ileostomy Luis Prieto1 Hanne Thorsen2 and Kristian Juul 3 Address 1Health Outcomes Consultant. C Rioja 7. 28750 San Agustin de Guadalix Spain institute of Public Health Department of General Practice University of Copenhagen Denmark and 3Ostomy Division Clinical Documentation Department Coloplast A S Holtedam 1 DK-3050 I lumlebi k Denmark Email Luis Prieto - prietol@ Hanne Thorsen - Kristian Juul - dkkju@ Corresponding author Published 12 October 2005 Received 09 May 2005 Health and Quality ofLife Outcomes 2005 3 62 doi l477-7525-3- Accepted 12 October 2005 62 This article is available from http contenV3 1 62 2005 Prieto et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Quality of life of stoma patients is increasingly being addressed in clinical trials. However the instruments used in the majority of these studies have not been validated specifically for stoma patients. The aim of this paper is to describe the development and validation of a quality-of-life instrument Stoma-QOL specifically for patients with colostomy or ileostomy. Methods Potential items were formulated in English on the basis of the results of a series of semistructured interviews with 169 adult stoma patients. The process resulted in a preliminary 37-item version which was translated into French German Spanish and Danish and administered repeatedly to 182 patients with colostomy or ileostomy. A psychometric selection of items was performed through Rasch Analysis. The measurement properties of the final