Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : A cross-sectional study of health-related quality of life deficits in individuals with comorbid diabetes and cancer | BioMed Central Health and Quality of Life Outcomes Research Open Access A cross-sectional study of health-related quality of life deficits in individuals with comorbid diabetes and cancer Samantha L Bowker1 2 Sheri L Pohar2 and Jeffrey A Johnson 1 2 Address department of Public Health Sciences Faculty of Medicine and Dentistry University of Alberta 13-103 Clinical Sciences Building Edmonton Alberta T6G 2G3 Canada and 2Institute of Health Economics 1200 10405 Jasper Avenue Edmonton Alberta T5J 3N4 Canada Email Samantha L Bowker - sbowker@ Sheri L Pohar - sherip@ JeffreyA Johnson - Corresponding author Published 22 March 2006 Received 14 January 2006 Accepted 22 March 2006 Health and Quality of Life Outcomes2006 4 17 doi 1477-7525-4-17 r This article is available from http content 4 1 17 2006Bowker et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Numerous studies have identified a reduced health related quality of life HRQL in patients that have either diabetes or cancer. We assessed the HRQL burden in patients with these comorbid conditions postulating that they would have even greater HRQL deficits. Methods Data from the Public Use File of the Canadian Community Health Survey PUF CCHS Cycle September 2000-November 2001 were used for this analysis. The total sample size of the CCHS PUF is 1 30 880 individuals. We used the Health Utilities Index Mark 3 HUI3 to assess HRQL in patients with 1 comorbid diabetes and cancer 2 diabetes alone 3 cancer alone and 4 no diabetes or cancer. Analysis of covariance was used to compare the mean overall HUI3 score controlling for age sex marital status body mass index BMI physical activity level smoking