Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Synchrony of change in depressive symptoms, health status, and quality of life in persons with clinical depression | BioMed Central Health and Quality of Life Outcomes Open Access Synchrony of change in depressive symptoms health status and quality of life in persons with clinical depression Paula H Diehr 1 Ann M Derleth1 Stephen P McKenna2 Mona L Martin Donald M Bushnell Gregory Simon and Donald L Patrick Address Department of Biostatistics F-670 HSB Box 357232 University of Washington Seattle WA 98195-7232 USA and 2Galen Research Enterprise House Manchester Science Park Lloyd Street North Manchester M15 6SE UK Email Paula H Diehr - pdiehr@ Ann M Derleth - aderleth@ Stephen P McKenna - SMcKenna@ Mona L Martin - martin@ Donald M Bushnell - bushnell@ Gregory Simon - Donald L Patrick - donald@ Corresponding author Published 25 April 2006 Received 02 February 2006 Health and Quality of Life Outcomes 2006 4 27 doi 1477-7525-4-27 Accepted 25 April 2006 This article is available from http content 4 1 27 2006 Diehr et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Little is known about longitudinal associations among measures of depression mental and physical health and quality of life QOL . We followed 982 clinically depressed persons to determine which measures changed and whether the change was synchronous with change in depressive symptoms. Methods Data were from the Longitudinal Investigation of Depression Outcomes LIDO . Depressive symptoms physical and mental health and quality of life were measured at baseline 6 weeks 3 months and 9 months. Change in the measures was examined over time and for
