Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Tooth loss and oral health-related quality of life: a systematic review and meta-analysis | Gerritsen et al. Health and Quality of Life Outcomes 2010 8 126 http content 8 1 126 HEALTH AND QUALITY of life outcomes REVIEW Open Access Tooth loss and oral health-related quality of life a systematic review and meta-analysis 1 21 3 1 Anneloes E Gerritsen P Finbarr Allen Dick J Witter Ewald M Bronkhorst Nico HJ Creugers Abstract Background It is increasingly recognized that the impact of disease on quality of life should be taken into account when assessing health status. It is likely that tooth loss in most cases being a consequence of oral diseases affects Oral Health-Related Quality of Life OHRQoL . The aim of the present study is to systematically review the literature and to analyse the relationship between the number and location of missing teeth and oral health-related quality of life OHRQoL . It was hypothesized that tooth loss is associated with an impairment of OHRQoL. Secondly it was hypothesized that location and distribution of remaining teeth play an important role in this. Methods Relevant databases were searched for papers in English published from 1990 to July 2009 following a broad search strategy. Relevant papers were selected by two independent readers using predefined exclusion criteria firstly on the basis of abstracts secondly by assessing full-text papers. Selected studies were grouped on the basis of OHRQoL instruments used and assessed for feasibility for quantitative synthesis. Comparable outcomes were subjected to meta-analysis remaining outcomes were subjected to a qualitative synthesis only. Results From a total of 924 references 35 were eligible for synthesis inter-reader agreement abstracts K full-texts K . Meta-analysis was feasible for 10 studies reporting on 13 different samples resulting in 6 separate analyses. All studies showed that tooth loss is associated with unfavourable OHRQoL scores independent of study location and OHRQoL instrument used. Qualitative synthesis showed that all 9 studies
