Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Impact of gastroesophageal reflux disease on daily life: the Systematic Investigation of Gastrointestinal Diseases in China (SILC) epidemiological study | Wang et al. Health and Quality of Life Outcomes 2010 8 128 http content 8 1 128 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Impact of gastroesophageal reflux disease on daily life the Systematic Investigation of Gastrointestinal Diseases in China SILC epidemiological study 1f 1 f 1f 1 X 1 2 3 4 Rui Wang Duowu Zou Xiuqiang Ma Yanfang Zhao Xiaoyan Yan Hong Yan Jiqian Fang Ping Yin Xiaoping Kang5 Qiang Li2 John Dent6 Joseph J Sung7 Katarina Hailing8 Saga Johansson8 Wenbin Liu9 Jia He1 Abstract Background Gastroesophageal reflux disease imposes a significant burden of illness in Western populations. However data on the impact of reflux symptoms on daily life in Asian populations are scarce. The current study aimed to evaluate the impact of GERD defined on the basis of symptoms on health-related quality-of-life HRQoL in individuals from five regions in China as part of the Systematic Investigation of Gastrointestinal Diseases in China SILC study. Methods In total 18 000 residents were randomly selected from across five regions of China and asked to complete a general information questionnaire and a Chinese version of the Reflux Disease Questionnaire RDQ . A randomly selected subsample of one-fifth of subjects 20 from each region completed Chinese versions of the 36-item self-administered SF-36 questionnaire and Epworth Sleepiness Scale ESS questionnaire. Reflux symptoms were defined as the presence of heartburn and or regurgitation. Symptom-defined GERD was diagnosed as mild heartburn and or regurgitation 2 days per week or moderate severe heartburn and or regurgitation 1 day a week based on the Montreal Definition of GERD for population-based studies. Results The response rate was for the total sample 16 091 18 000 and for the 20 subsample 3219 3600 . Meaningful impairment was observed in all 8 SF-36 dimensions in participants with symptom-defined GERD in 7 of the 8 SF-36 dimensions in participants with troublesome reflux symptoms and in
