Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Health-related quality of life in a clinical sample of obese children and adolescents | Riazi et al. Health and Quality of Life Outcomes 2010 8 134 http content 8 1 134 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Health-related quality of life in a clinical sample of obese children and adolescents Ătcond Pio 7Ì1Conio ch o lei cv r2 mho nil mi loc3 Ahrictitoci l-iccur4 Hoil .i A l l IZcmvid3 Aisane Riazi Sania Shakoor Isobel DUMUds Christine Libel Sheila A McKenzie Abstract Background Obesity affects ethnic minority groups disproportionately especially in the pediatric population. However little is known about the impact of obesity on health-related quality of life HRQoL in children and adolescents from mixed-ethnic samples. The purpose of this study was to 1 measure HRQoL in a mixed-ethnic clinical sample of obese children and adolescents 2 compare HRQoL assessments in obese participants and healthy controls and 3 compare HRQoL in obese children and adolescents according to their pubertal status. Methods A clinical sample of children and adolescents with obesity n 96 and healthy children and adolescents attending local schools n 444 completed the Pediatric Quality of Life Inventory PedsQL UK version 4 . Age-appropriate versions were self-administered by children and adolescents aged 8-18 years and interview administered to children aged 5-7 years. Multiple regression analyses controlling for age gender pubertal status and ethnicity were used to compare the PedsQL scores of the two samples. Results The clinical sample of obese children and adolescents had poorer HRQoL scores on all dimensions of the PedsQL compared to the healthy controls p . Subsequent analyses also demonstrated that in this sample of mixed-ethnic children and adolescents prepubescent obese children achieved the poorest scores in the emotional functioning dimension. Conclusions Obesity significantly impacts on physical emotional social and school functioning of mixed-ethnic children and adolescents. Clinicians need to be aware of the significant impact