Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Health status in routine clinical practice: validity of the clinical COPD questionnaire at the individual patient level | Kocks et al. Health and Quality of Life Outcomes 2010 8 135 http content 8 1 135 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Health status in routine clinical practice validity of the clinical COPD questionnaire at the individual patient level Janwillem WH Kocks Huib AM Kerstjens Sandra L Snijders Barbara de Vos Jacqueline J Biermann Peter van Hengel4 Jaap H Strijbos5 Henk EP Bosveld1 Thys van der Molen1 2 Abstract Background There is a growing interest to use health status or disease control questionnaires in routine clinical practice. However the validity of most questionnaires is established using techniques developed for group level validation. This study examines a new method using patient interviews to validate a short health status questionnaire the Clinical COPD Questionnaire CCQ at the individual patient level. Methods Patients with COPD who visited an outpatient clinic completed the CCQ before the consultation and the specialist physician completed it after the consultation. After the consultation all patients had a semi-structured in-depth interview. The patients CCQ scores were compared with those of the treating clinician and with mean scores from 5 clinicians from a pool of 20 who scored the CCQ after reading the transcript of the in-depth interviews only. Agreement was assessed using Lin s concordance correlation coefficient CCC and Blant and Altman plots. Interviews with patients with low agreement were reviewed for possible explanations. Results A total of 44 COPD patients 32 male mean age 66 years FEV1 45 of predicted participated. Agreement between the patients CCQ scores and those of the treating clinicians CCC and the mean score of the reviewing clinicians CCC was very high. No systematic error was detected. No explanation for individuals with low agreement was found. Conclusion The validity of the CCQ on the individual patient level as assessed by these methods is good. Individual health
