Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Gender differences in health related quality of life of young heroin users | Domingo-Salvany et al. Health and Quality of Life Outcomes 2010 8 145 http content 8 1 145 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Gender differences in health related quality of life of young heroin users 23 f V 2 4 I- f I - 5 2 6 Antònia Domingo-Salvany 1 M Teresa Brugal Gregorio Barrio Francisco González-Saiz M José Bravo Luis de la Fuente2 6 the ITINERE Investigators1 Abstract Background Health Related Quality of Life HRQL of opiate users has been studied in treatment settings where assistance for drug use was sought. In this study we ascertain factors related to HRQL of young opiate users recruited outside treatment facilities considering both genders separately. Methods Current opiate users 18-30 y were recruited in outdoor settings in three Spanish cities Barcelona Madrid Sevilla . Standardised laptop interviews included socio-demographic data drug use patterns health related issues the Severity of Dependence Scale SDS and the Nottingham Health Profile NHP . Results A total of 991 subjects 73 males mean age years were interviewed. The mean global NHP score differed by gender women sd men sd p . Multivariate analysis was implemented separately by gender variables independently related with global NHP score both for males and females were heroin and cocaine SDS scores. For women only other drug related variables alcohol intake and length of cocaine use were independently associated with their HRQL. HIV males who suffered an opiate overdose or had psychiatric care in the last 12 months perceived their health as poorer while those who had ever been in methadone treatment in the last 12 months perceived it as better. The model with both genders showed all factors for males plus quantity of alcohol and an interaction between gender and HIV status. Conclusions Heroin users were found to be at a considerable risk of impaired HRQL even in these young ages. A score approaching severity of dependence was .
